ceramide signaling pathway
| PAG Title | ceramide signaling pathway |
| PAG ID | WAG000218 |
| Type | P |
| Source Link |  BioCarta |
| Publication Reference | NA |
| PAG Description | Over 1,000 papers and reviews have been written about the role of ceramide in the production of programmed cell death or apoptosis. Ceramide is a sphingosine-based lipid-sigling molecule involved in the regulation of cellular differentiation, proliferation, and apoptosis. This diagram represents some of the current understanding of the cascades that couple ceramide to specific sigling pathways. These cascades illustrate that ceramide can be a growth stimulus or proapototic sigl. The ultimate ceramide action is determined within the context of other stimuli and by the subcellular topology of its production and is cell-type specific. |
| Species | Homo sapiens |
| nCoCo Score | 3,408 |
| Base PAG ID | WAG000218 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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